{"err":null,"data":[{"aliases":["speed","pepp","amphetamines","amphetamin","amfetamine","amph","hearts","pep"],"categories":["stimulant","habit-forming","common"],"dose_note":" NOTE: Street amphetamine is generally very impure, if you're working with a more pure chemical, lower doses will have greater effects.","formatted_aftereffects":{"_unit":"hours","value":"1-12"},"formatted_dose":{"Insufflated":{"Common":"25-40mg","Heavy":"75-100mg","Light":"15-25mg","Strong":"40-75mg"},"Oral":{"Common":"20-50mg","Heavy":"70-90mg","Light":"10-20mg","Strong":"50-70mg"}},"formatted_duration":{"_unit":"hours","Insufflated":"3-6","Oral":"4-8"},"formatted_effects":["Increased focus","abundance of energy","racing thoughts","elevated heartrate"],"formatted_onset":{"_unit":"minutes","Insufflated":"5-10","Oral":"15-30"},"links":{"experiences":"https://www.erowid.org/experiences/subs/exp_Amphetamines.shtml"},"name":"amphetamine","pretty_name":"Amphetamine","properties":{"after-effects":"1-12 hours.","aliases":["speed","pepp","amphetamines","amphetamin","amfetamine","amph","hearts","pep"],"avoid":"other stimulants, and depressants. Mixing depressants and stimulants is very rough on the heart. MXE is also to be avoided (possibility of serotonin syndrome).","categories":["stimulant","habit-forming","common"],"detection":"Blood: 12 hours. Saliva: ~3 days. Urine: 1-4 days. Hair: Up to 90 days.","dose":"Insufflated Light: 15-25mg Common: 25-40mg Strong: 40-75mg Heavy: 75-100mg | Oral Light: 10-20mg Common: 20-50mg Strong: 50-70mg Heavy: 70-90mg | NOTE: Street amphetamine is generally very impure, if you're working with a more pure chemical, lower doses will have greater effects.","duration":"Oral: 4-8 hours | Insufflated: 3-6 hours","effects":"Increased focus, abundance of energy, racing thoughts, elevated heartrate.","marquis":"Strong reddish orange - Dark reddish brown","onset":"Oral: 15-30 minutes. | Insufflated: 5-10 minutes.","summary":"A very popular CNS stimulant available on prescription and black markets. Recreational in high doses, producing mild euphoria and an abundance of energy. Popular in eastern europe and the US."},"pweffects":{"Abnormal heartbeat":"https://psychonautwiki.org/wiki/Abnormal_heartbeat","Analysis enhancement":"https://psychonautwiki.org/wiki/Analysis_enhancement","Anxiety":"https://psychonautwiki.org/wiki/Anxiety","Appetite suppression":"https://psychonautwiki.org/wiki/Appetite_suppression","Bronchodilation":"https://psychonautwiki.org/wiki/Bronchodilation","Cognitive euphoria":"https://psychonautwiki.org/wiki/Cognitive_euphoria","Cognitive fatigue":"https://psychonautwiki.org/wiki/Cognitive_fatigue","Compulsive redosing":"https://psychonautwiki.org/wiki/Compulsive_redosing","Dehydration":"https://psychonautwiki.org/wiki/Dehydration","Depression":"https://psychonautwiki.org/wiki/Depression","Focus enhancement":"https://psychonautwiki.org/wiki/Focus_enhancement","Frequent urination":"https://psychonautwiki.org/wiki/Frequent_urination","Increased blood pressure":"https://psychonautwiki.org/wiki/Increased_blood_pressure","Increased heart rate":"https://psychonautwiki.org/wiki/Increased_heart_rate","Increased libido":"https://psychonautwiki.org/wiki/Increased_libido","Increased perspiration":"https://psychonautwiki.org/wiki/Increased_perspiration","Irritability":"https://psychonautwiki.org/wiki/Irritability","Memory enhancement":"https://psychonautwiki.org/wiki/Memory_enhancement","Motivation enhancement":"https://psychonautwiki.org/wiki/Motivation_enhancement","Nausea":"https://psychonautwiki.org/wiki/Nausea","Stimulation":"https://psychonautwiki.org/wiki/Stimulation","Teeth grinding":"https://psychonautwiki.org/wiki/Teeth_grinding","Temporary erectile dysfunction":"https://psychonautwiki.org/wiki/Temporary_erectile_dysfunction","Thought acceleration":"https://psychonautwiki.org/wiki/Thought_acceleration","Thought deceleration":"https://psychonautwiki.org/wiki/Thought_deceleration","Thought organization":"https://psychonautwiki.org/wiki/Thought_organization","Vasoconstriction":"https://psychonautwiki.org/wiki/Vasoconstriction","Wakefulness":"https://psychonautwiki.org/wiki/Wakefulness"},"sources":{"_general":["Treatment for amphetamine dependence and abuse. - http://www.ncbi.nlm.nih.gov/pubmed/11687171","Comparative and interactive human psychopharmacologic effects of ketamine and amphetamine: implications for glutamatergic and dopaminergic models - https://www.ncbi.nlm.nih.gov/pubmed/16143730","Treatment for amphetamine dependence and abuse. - https://www.ncbi.nlm.nih.gov/pubmed/11687171","Comparative and interactive human psychopharmacologic effects of ketamine and amphetamine: implications for glutamatergic and dopaminergic model ps... - https://www.ncbi.nlm.nih.gov/pubmed/16143730","The beta-lactam antibiotic ceftriaxone inhibits physical dependence and abstinence-induced withdrawal from cocaine, amphetamine, methamphetamine, a... - https://www.ncbi.nlm.nih.gov/pubmed/18342307","A comparison of methylphenidate-, amphetamine-, and methamphetamine-induced hyperthermia and neurotoxicity in male Sprague-Dawley rats during the w... - https://www.ncbi.nlm.nih.gov/pubmed/22289608","Enduring changes in brain and behavior produced by chronic amphetamine administration: a review and evaluation of animal models of amphetamine psyc... - https://www.ncbi.nlm.nih.gov/pubmed/3527341","L-DOPA exacerbates amphetamine-induced dopamine depletion. - https://www.ncbi.nlm.nih.gov/pubmed/9565967","Amphetamines in the treatment of Parkinson's disease. - http://www.ncbi.nlm.nih.gov/pubmed/1097600","Effect of dopamine D2/D3 receptor antagonist sulpiride on amphetamine-induced changes in striatal extracellular dopamine. - http://www.ncbi.nlm.nih.gov/pubmed/11343690","Behavioral and neuropharmacological analysis of amphetamine and 2,5-dimethoxy-4-methylamphetamine in rats. - http://www.ncbi.nlm.nih.gov/pubmed/1208759","Identification of di(beta-phenylisopropyl)amine as the main ingredient in illicit amphetamine tablets. - http://www.ncbi.nlm.nih.gov/pubmed/12645186","Long-term opiate effects on amphetamine-induced dopamine release in the nucleus accumbens core and conditioned place preference. - http://www.ncbi.nlm.nih.gov/pubmed/14751461","Microglial activation is a pharmacologically specific marker for the neurotoxic amphetamines. - http://www.ncbi.nlm.nih.gov/pubmed/15337264","Caffeine induces differential cross tolerance to the amphetamine-like discriminative stimulus effects of dopaminergic agonists. - http://www.ncbi.nlm.nih.gov/pubmed/15833596","Christmas gingerbread (Lebkuchen) and Christmas cheer--review of the potential role of mood elevating amphetamine-like compounds formed in vivo and... - http://www.ncbi.nlm.nih.gov/pubmed/16007907","Dual intoxication with diazepam and amphetamine: this drug interaction probably potentiates myocardial ischemia. - http://www.ncbi.nlm.nih.gov/pubmed/17320309","Update on amphetamine neurotoxicity and its relevance to the treatment of ADHD. - http://www.ncbi.nlm.nih.gov/pubmed/17606768","Mephedrone, compared with MDMA (ecstasy) and amphetamine, rapidly increases both dopamine and 5-HT levels in nucleus accumbens of awake rats. - http://www.ncbi.nlm.nih.gov/pubmed/21615721","Aminorex, a metabolite of the cocaine adulterant levamisole, exerts amphetamine like actions at monoamine transporters. - http://www.ncbi.nlm.nih.gov/pubmed/24296074","Long-lasting effects of escalating doses of d-amphetamine on brain monoamines, amphetamine-induced stereotyped behavior and spontaneous nocturnal l... - http://www.ncbi.nlm.nih.gov/pubmed/2440058","Amphetamine modulates excitatory neurotransmission through endocytosis of the glutamate transporter EAAT3 in dopamine neurons. - http://www.ncbi.nlm.nih.gov/pubmed/25033183","Acute methoxetamine and amphetamine poisoning with fatal outcome: a case report. - http://www.ncbi.nlm.nih.gov/pubmed/25060403","[Antitussive effect of amphetamine]. - http://www.ncbi.nlm.nih.gov/pubmed/552131","Amphetamine-clonidine interaction on neurotransmission in the vas deferens of the rat. - http://www.ncbi.nlm.nih.gov/pubmed/6098834","Self-injection of amphetamine directly into the brain. - http://www.ncbi.nlm.nih.gov/pubmed/6415748","Amphetamine-induced analgesia does not involve brain opioids. - http://www.ncbi.nlm.nih.gov/pubmed/6468501","Amphetamine-metabolites of deprenyl involved in protection against neurotoxicity induced by MPTP and 2'-methyl-MPTP. - http://www.ncbi.nlm.nih.gov/pubmed/7931228","L-DOPA exacerbates amphetamine-induced dopamine depletion. - http://www.ncbi.nlm.nih.gov/pubmed/9565967","Long-lasting psychotomimetic consequences of repeated low-dose amphetamine exposure in rhesus monkeys. - http://www.ncbi.nlm.nih.gov/pubmed/9885781","Use of naltrexone has been found to successfully aid in recovery from amphetamine addiction - http://ajp.psychiatryonline.org/doi/abs/10.1176/appi.ajp.2008.08020304","According to drugs.com 's interaction checker, there is a potential for serotonin syndrome when mixing amphetamines and ssri's. The threshold dose for danger however is unknown. https://www.drugs.com/interactions-check.php?drug_list=2543-0,679-0","Amphetamine has a half life of 7-31 hours: Mosby's Dental Drug Reference Ninth Edition 2010","Pregnancy category C according to the FDA. Evidence has shown usage during pregnancy can cause premature birth, low birthweight, and withdrawal syndrome in the baby. This occurs more often in abuse of adderall. Recommendation is to consult with a physician if you are pregnant.","Pregnancy category C according to the FDA. - https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/011522s040lbl.pdf"]}}]}