{"err":null,"data":[{"categories":["opioid","habit-forming","depressant","common"],"formatted_aftereffects":{"_unit":"hours","value":"1-48"},"formatted_dose":{"Oral":{"Common":"10-20mg","Light":"5-10mg","Strong":"20-35mg+"}},"formatted_duration":{"_unit":"hours"},"formatted_effects":["Euphoria","Dry Mouth","Mood lift","Itchiness","Relaxant","Constipation","Pupil constriction","Analgesia"],"formatted_onset":{"_unit":"minutes","value":"45-120"},"links":{"experiences":"https://www.erowid.org/experiences/subs/exp_Methadone.shtml"},"name":"methadone","pretty_name":"Methadone","properties":{"after-effects":"1-48 hours.","avoid":"All other CNS depressants","bioavailability":"Oral 75-97% (Mean 86%) | Rectal 70-81% (Mean 76%)","categories":["opioid","habit-forming","depressant","common"],"dose":"Light: 5-10mg Common: 10-20mg Strong: 20-35mg+ NOTE: these doses are not intended for opioid-naïve users. 40mg could be lethal for a naïve user. Always start low and titrate /slowly/","duration":"Oral 6-12 hours. NOTE: Can last much longer. Mostly dependant if using Chronically or not.","effects":"Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.","half-life":"12-18 hours on the first dose 13-47 on concurrent","onset":"45-120 minutes.","summary":"A synthetic opioid drug used as an analgesic and is often used in detoxification off of other opioids. As it has a much longer half-life."},"sources":{"_general":["Methadone trials have proven successful in treating Heroin addiction - http://jamanetwork.com/journals/jama/article-abstract/656315"]}}]}