Index > Factsheets > Aspirin


SummaryA widely used anti-inflammatory and blood-thinner produced by acetylation of the naturally occurring salicyclic acid. Part of the nonsteroidal antiinflammatory class of drugs, a cyclooxygenase inhibitor. Very common over-the-counter pain reliever and fever reducer. Also used in smaller doses to lower risk of heart attack.
DoseOral Threshold: 50mg Light: 75mg-81mg Common: 325mg-650mg Heavy: 1.6g
NOTE: Aspirin is known to be dangerous in dosages of 4g and above
Onset30-90 minutes.
Duration(Dose-Dependent) 2-3h (for low doses), 15-30h (for large doses)
EffectsAnalgesia, Antipyresis, Anti-inflammation, Antiaggregation
AvoidAcetazolamide, Ammonium Chloride, Alcohol, Tolbutamide, Chlorpropamide, Warfarin, Methotrexate, Phenytoin, Probenecid, Valproic Acid, Other NSAIDs, Corticosteroids, Spironolactone, Penicillin G, Vitamin C
BioavailabilityOral: 55.8-74%.