Index > Factsheets > Caffeine


SummaryCaffeine is a a CNS stimulant, and also the most widely used psychoactive substance in the world. It is legal and unregulated in most parts of the world, and is found in many commonly sold products. It has a good safety profile, though regular heavy use can cause physical dependence and contribute to certain medical conditions.
DoseThreshold: 10-20mg Light: 20-75mg Common: 75mg-250mg Strong: 250-400mg Heavy: 400mg+
NOTE: The lethal dose for caffeine starts at approximately 3g. The average cup of coffee contains roughly 75-150mg of caffeine.
Onset5-10 minutes
Duration1.5-5 hours
Effectselevated heartrate, increase in cognitive abilities, physical agitation, panicked thinking, racing thoughts, uncomfortable bodyload
After-effects3-4 hours
BioavailabilityOrally it varies from around 77%-99%