↳ Index > Factsheets > Clomethiazole
| Clomethiazole | Info |
|---|
| Summary | Structurally related to Thiamine (vitamin B1), but with binding potential at the GABAa site, which causes it to produce effects most like those of a barbiturate: an effective sedative and hypnotic. Originally developed by Hoffman-LaRoche in the 1930s, it has seen use as a treatment for acute alcohol withdrawal. |
| Dose | Oral Threshold: 100mg Light: 100-150mg Common: 150-200mg Heavy: 200mg+ |
| Onset | 15-40 minutes. |
| Duration | 5-8 hours. |
| Warning | The normal amount in capsules is 192mg's. Treat this more as a barbiturate than a benzodiazepine, as the toxicology for this substance is rather lacking. |
| Categories | depressant research-chemical habit-forming tentative |
| Effects | Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic. |
| After-effects | 1-16 hours. |