Index > Factsheets > Doxylamine


SummaryA first generation antihistamine and anticholinergic, originally used to treat nausea and itching, and later as a sleep aid. Causes drowsiness, and delirium in overdose. Sometimes used with opioids to combat nausea and potentiate effects.
DoseThreshold: 10mg Light: 75-200mg Common: 200-350mg Heavy: 350mg+
Onset20-30 minutes
Duration6-8 hours
WarningAs with other first generation antihistamines, if you take too much you could have a delirant like experience.
After-effects1-6 hours.