↳ Index > Factsheets > Fentanyl
| Fentanyl | Info |
|---|
| Summary | Fentanyl is a synthetic opiate analgesic with a rapid onset and short duration of action. It is a strong agonist at the μ-opioid receptors and is historically used to treat breakthrough pain. Fentanyl is approximately 100 times more potent than Morphine, and is commonly used as a patch. Sometimes used as an adulterant for heroin, which has led to many overdose deaths. |
| Dose | Intranasal Light: 10-25ug Common: 25-50ug Strong: 50-75ug+ Transdermal Light: 12.5ug/hr Common: 25-50ug/hr Strong: 50-100ug/hr NOTE: Due to Fentanyl's high potency, it is incredibly difficult to measure safely, and so can easily lead to overdose. |
| Onset | Transdermal: 90-180 minutes. Buccal: 15-30 ninutes Insufflated: 5-15 minutes. |
| Duration | Transdermal: 48-72 hours. | Buccal: 1-4 hours. | Insufflated: 1-4 hours. |
| Effects | Analgesia, euphoria, feelings of relaxation, sedative effects, changes in focus, attention, respiratory depression, nausea, constipation, dry mouth, somnolence, confusion, weakness, sweating, fatigue, dizziness, anxiety |
| Categories | opioid habit-forming depressant |
| Aliases | fent |
| Bioavailability | Sublingual/Buccal 50% | Insufflated 70% | Transdermal 92% |
| Warning | Risk of post-acute withdrawal effects, including depression, anxiety disorder, psychosis, suicidal ideation in extreme cases. |