↳ Index > Factsheets > Methadone
| Methadone | Info |
|---|
| Summary | A synthetic opioid drug used as an analgesic and is often used in detoxification off of other opioids. As it has a much longer half-life. |
| Dose | Light: 5-10mg Common: 10-20mg Strong: 20-35mg+ NOTE: these doses are not intended for opioid-naïve users. 40mg could be lethal for a naïve user. Always start low and titrate /slowly/ |
| Onset | 45-120 minutes. |
| Duration | Oral 6-12 hours. NOTE: Can last much longer. Mostly dependant if using Chronically or not. |
| Categories | opioid habit-forming depressant common |
| Avoid | All other CNS depressants |
| Bioavailability | Oral 75-97% (Mean 86%) | Rectal 70-81% (Mean 76%) |
| Half-life | 12-18 hours on the first dose 13-47 on concurrent |
| Effects | Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia. |
| After-effects | 1-48 hours. |