Index > Factsheets > Oxymorphone


SummaryA powerful semisynthetic opioid analgesic also known as opana. A derivative of morphine it is approximately ten times as potent. Has a low oral bioavailability, and as such it is usually insufflated or taken rectally.
DoseOral Low: 5-7.5mg Common: 10-20mg Heavy: 20mg+
Insufflated Low: 2-4mg Common: 4-6mg Heavy: 6-10mg+
OnsetOral_IR: 20-40 minutes
Oral_ER: 60-90 minutes.
Insufflated: 1-5 minutes
Plugged: 15-30 minutes.
IV: 0-1 minutes
DurationOral_IR: 4-8 hours | Oral_ER: 6-14 hours | Insufflated 5-8 hours | Plugged: 4-7 hours | IV: 2-4 hours. | Note: Tolerance + contents in your stomach can cause this to be quite different.
AvoidAll other CNS depressants.
WarningNOTE: There has been reports of a rare blood disorder from Intravenous use of Oxymorphone ER. Take this into consideration before taking the drug this way.
BioavailabilityIntranasal: 43%, Oral: 10-20%, Rectal: 10%
EffectsEuphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.
After-effects1-12 hours.