↳ Index > Factsheets > Tramadol
| Tramadol | Info |
|---|
| Summary | A synthetic opioid analgesic, tramadol is used to treat moderate pain and can be considered a medium-strength opioid. Tramadol also has the unusual effect of being a serotonin releasing agent and a serotonin reuptake inhibitor, and as a consequence should not be taken in excess due to the risk of serotonin syndrome. Risk of seizures above 300mg doses. |
| Dose | Oral Light: 50-100mg Common: 100-250mg Heavy: 250-400mg NOTE: Tramadol has a ceiling dose, where recreational effects are not increased. Risk of seizure at doses over 300mg. Tramadol decreases the seizure threshold, use extreme caution. Dosing insufflated is ineffective. |
| Onset | 1 hour first effects, reaching peak blood concentration at 4 hours. |
| Duration | 5-7 hours |
| Effects | euphoria, elevated mood, overall feeling of contentedness, itching, drowsiness, vomiting, urinary retention, nausea, constipation, risk of seizure above 300mg |
| Avoid | benzos, alcohol, and other opiates |
| Categories | opioid habit-forming depressant common |
| Bioavailability | Oral 68-72% | Rectal 77% |
| Aliases | tram |
| After-effects | 1-12 hours. |